Brain-CODE Neuroinformatics Platform

Brain-CODE is used by more than 450 researchers at over 40 institutions across Canada to collect, analyze and share their data.

Brain-CODE is the Ontario Brain Institute's (OBI) state-of-the-art neuroinformatics platform. It is designed to support the collection, storage, federation, sharing and analysis of different data types across several brain disorders, in order to understand the common underlying causes of brain dysfunction and support development of novel approaches to treatment.


Brain-CODE provides researchers with access to aggregated datasets that they otherwise could not obtain independently. The platform incentivizes data sharing and collaboration and facilitates analyses both within and across disorders and across a wide array of data types, including clinical, neuroimaging and molecular. The Brain-CODE system architecture provides the technical capabilities to support (1) consolidated data management to securely capture, monitor and curate data, (2) privacy and security best-practices, and (3) interoperable and extensible systems that support harmonization, integration, and query across diverse data modalities and linkages to external data sources. Brain-CODE currently supports collaborative research networks focused on various brain conditions, including neurodevelopmental disorders, cerebral palsy, neurodegenerative diseases, epilepsy, mood disorders and concussion. These programs are generating large volumes of data that are integrated within Brain-CODE to support scientific inquiry and analytics across multiple brain disorders and modalities. By providing access to very large datasets on patients with different brain disorders and enabling linkages to provincial, national and international databases, Brain-CODE helps to generate new hypotheses about the biological bases of brain disorders, and ultimately promote new discoveries to improve patient care.

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